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863: Abeta Peptide

Closed since about 12 years ago

Intermediate Overall Prediction

Summary

Created
March 21, 2014
Expires
Max points
100
Description

This short peptide is a fragment of a larger protein found in the membrane of neurons. The Abeta peptide is a product of natural proteolysis reactions in brain tissue, but accumulation of this peptide has been linked to Alzheimer's disease. Abeta is very flexible in solution and is known to sample both alpha-helix and beta-sheet conformations, though little else is known about the full range of structures adopted by Abeta. Help us find the highest-scoring structure(s) of this protein!

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