886: CASP11 Target T0759: Server Models

Closed since almost 12 years ago

Summary

• Created: May 03, 2014
• Expires: May 10, 2014 at 20:00 UTC
• Max points: 100

Description

This is the first CASP11 Foldit puzzle! This puzzle has 101 residues, and we've provided you with 5 Robetta server models (all generated from the same homology template). Restart the puzzle to cycle through the alternate starting structures.

Top groups

• 11. Repro-men 11 pts. 9,172
• 12. Deleted group pts. 9,134
• 13. FoldIt@Netherlands 7 pts. 9,076
• 14. HMT heritage 5 pts. 9,013
• 15. SETI.Germany 4 pts. 9,009
• 16. Freedom Folders 3 pts. 8,996
• 17. Italiani Al Lavoro 2 pts. 8,977
• 18. It's over 9000! 1 pt. 8,956
• 19. Brony@Home 1 pt. 8,876
• 20. Koronan ChemistryUO Poland 1 pt. 8,875

Top soloists

• 11. gloverd 81 pts. 9,310
• 12. johnmitch 79 pts. 9,300
• 13. spvincent 77 pts. 9,296
• 14. Timo van der Laan 75 pts. 9,296
• 15. Grom 74 pts. 9,295
• 16. nicobul 72 pts. 9,294
• 17. Antibrad 70 pts. 9,282
• 18. gmn 69 pts. 9,277
• 19. Susume 67 pts. 9,271
• 20. pauldunn 66 pts. 9,270

Comments

[wisky]

In the puzzle description, you say this target has 109 residues.

In game, it has 101.

One of these is a mistake, and I hope it's the description…

[wisky]

Could be a possible histidine tag removal? No clue.

[beta_helix]

You can see that the RosettaServer ignored the first 8 residues:
http://rosettaserver.bakerlab.org/results.jsp?id=48098&p=1

I'll update the description, thanks for the catch!

[wisky]

Thanks, beta_helix. Scared me for a bit there ;)

[Steven Pletsch]

Is there a SAM prediction for his puzzle ?

[beta_helix]

There is a SAM prediction, but that is for the full length of the target (including the his tag) so the numbering is all off.

It's probably easier to use the RosettaServer's secondary structure prediction (from PSIPRED): http://rosettaserver.bakerlab.org/results.jsp?id=48098&p=1

but here is the SAM sequence logo in case you are interested:

compbio.soe.ucsc.edu

T0759.dssp-ehl2-logo.pdf

[Steven Pletsch]

Thank you both are helpful :)

[jeff101]

It would be helpful if you would list the starting scores for each of the 5 models shown at: http://rosettaserver.bakerlab.org/results.jsp?id=48098&p=1
Perhaps for future puzzles, you could list the score for each model under its image on pages like this. You could also do like structure.SetNote(1,'Model X 5238.408') to set a note for amino acid #1 in each structure saying which model it represents.

So far I have seen the following starting scores for puzzle 886:
5238.408
7097.759
7232.753
Can you list the remaining scores and to which model each of the 5 scores corresponds?

Thanks!

[spmm]

The structure number is listed in the tab popup, but not the start score. Only five models without alignments is a bit luxurious :)

[jeff101]

Thanks, spmm. Now I see the model/structure numbers when I tab on amino acids. I also noticed that on my slower machines when I press "Reset Puzzle", the new model number appears like a level up/down message and then quickly disappears.

So here are the 5 models for 886 with their starting scores:
1 7097.759
2 6755.029
3 5238.408
4 7232.753
5 7116.894