921: CASP11 Refinement Target: TR280

Closed since almost 12 years ago

Summary

• Created: June 20, 2014
• Expires: June 25, 2014 at 10:00 UTC
• Max points: 100

Description

This CASP refinement target has 96 residues, and we've been told that ~59% of this starting structure is correct. High Wiggle Power has been enabled for this puzzle.

Top groups

• 11. Italiani Al Lavoro 3 pts. 9,083
• 12. HMT heritage 2 pts. 9,024
• 13. Deleted group pts. 8,986
• 14. CHNO Junkies 1 pt. 8,974
• 15. Repro-men 1 pt. 8,889
• 16. Natural Abilities 1 pt. 8,857
• 17. SETI.Germany 1 pt. 8,797
• 18. Team Schleswig-Holstein 1 pt. 8,393
• 19. Crunching Family 1 pt. 7,867
• 20. DSN @ Home 1 pt. 7,838

Top evolvers

• 1. MaartenDesnouck 100 pts. 9,520
• 2. Galaxie 87 pts. 9,518
• 3. jamiexq 74 pts. 9,516
• 4. gmn 64 pts. 9,516
• 5. alwen 54 pts. 9,515
• 6. smilingone 46 pts. 9,451
• 7. spdenne 38 pts. 9,442
• 8. reefyrob 32 pts. 9,441
• 9. bertro 27 pts. 9,432
• 10. LociOiling 22 pts. 9,417

Comments

[frood66]

the statement.."~59% of this starting structure is correct."

Can we please have a full explanation of what this means - a link that can be refered to on all refinement puzzles?

There is a lack of understanding amongst vets (let alone newbs)

[wisky]

Are we also going to get TR0780, as it's part of the same protein?

[wisky]

en.wikipedia.org

Global distance test

The global distance test (GDT), also written as GDT_TS to represent "total score", is a measure of similarity between two protein structures with known amino acid correspondences (e.g. identical amino acid sequences) but different tertiary structures. It is most commonly used to compare the results of protein structure prediction to the experimentally determined structure as measured by X-ray crystallography, protein NMR, or, increasingly, cryoelectron microscopy. The metric was developed by Ada...

The "~59%" comes straight from the CASP website, referring to roughly a 59% (.59) GDT-HA score.

[beta_helix]

TR780 will be posted soon (closer to when 917 closes)

Thanks for posting that GDT link, wisky!