Lab Report #31: Breaking it down

Started by bkoep

bkoep Staff Lv 1

A new paper shows how scientists can now make proteins that bind a bunch of different targets. How did they do it — and what does this breakthrough mean for Foldit? In this video, we breakdown a recent breakthough in protein design.

NEWS

PUZZLE UPDATES

  • Binder design for CD22, TGF-beta receptor, and other hard targets
  • Electron density reconstruction
  • Small molecule design
  • Symmetric protein design

DESIGN OF THE MONTH

  • A symmetric tetramer design by BootsMcGraw in Puzzle 2121. Boots uses an extensive H-bond Network to satisfy buried polar residues at the symmetric interface. See for yourself in the Design of the Month sandbox puzzle.