HIV Fight!

[Rav3n_pl]

Hello.
For all those who want to fight HIV I opened contest :D
http://fold.it/portal/node/988310
I`m sure there was opened same puzzles many time but… CASP9 ends ;]
Feel free to join!
It ends at 31.

[Rav3n_pl]

Some links to knowh what we dealing at :)

en.wikipedia.org

HIV-1 protease

HIV-1 protease (PR) is a retroviral aspartyl protease (retropepsin), an enzyme involved with peptide bond hydrolysis in retroviruses, that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins (namely, Gag and Gag-Pol) at nine cleavage sites to create the mature protein components of an HIV virion, the infectious form of a virus outside of the host cell. Without effective HIV protease, HIV virions remain uninfectio Mature HIV ...

http://www.pdb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb6_1.html

http://www.proteopedia.org/wiki/index.php/HIV-1_protease

Or google for more :D

[Rav3n_pl]

Great job everyone :D
Bletchley Park beat us all for almost 100pts!

Bletchley Park 9864
Renton 9767
infjamc 9645
rav3n_pl 9542
Marie Suchard 9465
mimi 9442
adrock2999 9416
RyeSnake 9403
aendgraend 9394
Tlaloc 9370
phireg 9363
vixynn 9288

:D
Can someone compare results to other HIV puzzles?