Thanks for taking our understanding of the game into account !
I would say: be conservative for old established terms, innovative, short but more or less scientific and "self-explaining" for new ones.
-Conservative: there is a lot of foldit "literature", we want to still understand the wiki, old puzzles and recipes (so don't change too much the vocabulary, let the language go it's own way). Example: "Fuzing" is ok. Most glossary is explained in the wiki, so it's always better not to propose new terms for existing ones.
Moreover, for recipes, I use the title and description of the puzzles in order for the recipe to behave accordingly (for example is searches for "design" or "filter" in order to adapt options): better not to change too often.
This is particularly important for the parameters of the commands and the command names.
-scientific: as much as possible, use one of the possible scientific terms (the one that is the closed to child understanding). We like to learn something and to be able to speak about it with appropriate terms. For new tools, try to select one short simplified "scientific" term (the one you would use for 18 year old students).
-Simple, short terms: "helix" and not "beta helix", "hydrophobic", "cut", "mutate", "rebuild" …
-practical as "backbone", "sidechain", helix, "x-ray tunnel" view, "recipe", "cookbook"
-visual as "helix", "red", "orange", "large", "parallel", "aligned" etc.
-unique ! select one short term from now for ever ("helix", "segment" …)
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These have long been confusing for me: if possible, select one unique per unique concept
-"ligand" / "drug" / "molecule" / (latest) segment …
-residue / segment
-score / energy score
-loop / disordered
-alpha, beta, … stand …, residue
-some of the view options: isosurface, constraints
-I couldn't translate some terms to French like "shake", "wiggle", "tweak"
-ideal, idealize, remix, rebuild, abego, "low/medium/auto" "wiggle power"
-track / client
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Conclusion: don't change too much "old thinks" but it's a good idea to adapt and change the names of the new thinks (for example there was no problem to change the name of experimental to pilot etc - better to take some time to find a good name "with us" the first year of a new product). It's still ok to change the names of confusing terms like "ideal" etc.