Bletchley Park Lv 1
Is there a reason behind not being able to freeze sidechains in KCNT2 puzzles ?
I would expect one to be able to freeze and unfreeze unlocked sidechains.
Is there a reason behind not being able to freeze sidechains in KCNT2 puzzles ?
I would expect one to be able to freeze and unfreeze unlocked sidechains.
Hi @"Bletchley Park" I have activated the freeze/unfreeze action for the upcoming Small Molecule puzzles. The only reason this wasn't active to begin with is because side chains had predominantly remained locked until later in the puzzle series if unlocked at all. This mostly depends on what our collaborators are looking for. In the case of the current KCNT2 puzzles, our collaborators wanted to have a bit more flexibility around the pocket.
Cheers!
Sciren
Thank you @Sciren !
Torsions still appear in frozen ligand
@"Bruno Kestemont" what exactly do you mean by that ? The K-option torsions arrows ?
When freezeing the ligand, then wiggle all, the ligand still changes (for example, Torsion quality can change)
Thus: Freezed ligand is'nt freezed.