Clients on evolver mode ask for much more resources than solo clients. After several days running recipes, the client turns slower and slower with larger times of "not responding" periodes, certainly on big or ED puzzles.
(Windows)
On ligand puzzle as well. Even stopping recipes, trying to share or moving the puzzle on the screen takes minutes to >10 minutes.
It's very strange and unconfortable (it discourage to evolve puzzles).
Thanks for bringing this up again, Bruno.
Are you on Windows?
Yes Windows 10. Same on 2 different computers. Today, it took >3 hours to share a ligand puzzle solution, and it never shared.
I forced going out. I came back, tried to share again, it shared in about 5 minutes.
Its much slower after running a recipe for several hours.
Only actions on screen (saving, sharing, editing) are very slow (recipes work well). Hand fold seems to work normally at start, but all GUI action takes a while after a recipe took actions for several hours.
Has anyone else noticed this in Windows or a different OS?
Are there any specific scripts that seem to always cause this?
Yes, I notice that as well. See also my comment on the load time for the Compound Library. I run a variety of scripts and usually the client dies at some point after a day or two. I then completely restart my PC and get going again.
I noticed some time before it dies that the bond animation becomes stuttering or completely stops. Could be a threading issue ?
I also notice that when running multiple clients, if I open them 'in the wrong sequence' at some point one of those clients no longer accepts macro command shortcuts although I can move the protein around with the mouse. In that situation the only thing I can do with the keyboard is use ALT-X to quit the client.
All of these issues to me sound like symptoms of a threading bug.
Thank you for this BP, hopefully we'll be able to pinpoint what is causing this!
1) The slow interface evolver client seems to apply only for the first client for each puzzle. I opened 2 other clients for the same puzzle and these behaved normally.
2) It doesn't appear for all puzzles types. At least for ED ans Ligand ones, not for small puzzles like several revisiting ones (evolving 2674 is ok). And not on all computers (mainly on a 8 years old computer).