Small Molecule Design puzzles

CASP10 Kinect CASP ROLL Hand-Folding CASP11 Predicted Contacts Pilot Overall Beginner Novice Intermediate Advanced Design Small Molecule Design Prediction Symmetry Electron Density

Players design inhibitors or modulators for folded proteins -- no protein folding required! Create new small molecules by modifying individual atoms, adding and deleting fragments, and using reaction-based design for tractable lab testing. The number of possibilities is estimated at 10^60!

Leaderboard: top small molecule design soloists

  1. Avatar for Serca 131. Serca Lv 1 3
  2. Avatar for TranKhue 131. TranKhue Lv 1 3
  3. Avatar for awa14 131. awa14 Lv 1 3
  4. Avatar for Alice_Tomonaga 131. Alice_Tomonaga Lv 1 3
  5. Avatar for CaptainCupcake 131. CaptainCupcake Lv 1 3
  6. Avatar for ProfVince 131. ProfVince Lv 1 3
  7. Avatar for Wildice1100 131. Wildice1100 Lv 1 3
  8. Avatar for Cagdason 138. Cagdason Lv 1 2
  9. Avatar for mshifflett 138. mshifflett Lv 1 2
  10. Avatar for LadyCrazy 138. LadyCrazy Lv 1 2

Recent small molecule design puzzles

Puzzle Status
2748: SF-1 Round 6 Closed since 3 days ago
2745: LRH-1 Round 6 Closed since 7 days ago
2742: SF-1 Round 5 Closed since 17 days ago