Small Molecule Design puzzles

CASP10 Kinect CASP ROLL Hand-Folding CASP11 Predicted Contacts Pilot Overall Beginner Novice Intermediate Advanced Design Small Molecule Design Prediction Symmetry Electron Density

Players design inhibitors or modulators for folded proteins -- no protein folding required! Create new small molecules by modifying individual atoms, adding and deleting fragments, and using reaction-based design for tractable lab testing. The number of possibilities is estimated at 10^60!

Leaderboard: top small molecule design soloists

  1. Avatar for ucad
    1. ucad Lv 1
    1,990
  2. Avatar for Floddi 2. Floddi Lv 1 1,766
  3. Avatar for gmn 3. gmn Lv 1 1,662
  4. Avatar for Bruno Kestemont 4. Bruno Kestemont Lv 1 1,658
  5. Avatar for arotomic 5. arotomic Lv 1 1,521
  6. Avatar for alcor29 6. alcor29 Lv 1 1,395
  7. Avatar for Bletchley Park 7. Bletchley Park Lv 1 1,299
  8. Avatar for BootsMcGraw 8. BootsMcGraw Lv 1 1,296
  9. Avatar for LociOiling 9. LociOiling Lv 1 1,259
  10. Avatar for carxo 10. carxo Lv 1 1,146

Recent small molecule design puzzles

Puzzle Status
2748: SF-1 Round 6 Open for the next 6 days
2745: LRH-1 Round 6 Open for the next 1 day
2742: SF-1 Round 5 Closed since 8 days ago
2739: LRH-1 Round 5 Closed since 15 days ago
2736: SF-1 Round 4 Closed since 22 days ago