Small Molecule Design puzzles

CASP10 Kinect CASP ROLL Hand-Folding CASP11 Predicted Contacts Pilot Overall Beginner Novice Intermediate Advanced Design Small Molecule Design Prediction Symmetry Electron Density

Players design inhibitors or modulators for folded proteins -- no protein folding required! Create new small molecules by modifying individual atoms, adding and deleting fragments, and using reaction-based design for tractable lab testing. The number of possibilities is estimated at 10^60!

Leaderboard: top small molecule design soloists

  1. Avatar for ucad
    1. ucad Lv 1
    1,996
  2. Avatar for Bruno Kestemont 2. Bruno Kestemont Lv 1 1,681
  3. Avatar for gmn 3. gmn Lv 1 1,657
  4. Avatar for Floddi 4. Floddi Lv 1 1,566
  5. Avatar for arotomic 5. arotomic Lv 1 1,544
  6. Avatar for alcor29 6. alcor29 Lv 1 1,474
  7. Avatar for LociOiling 7. LociOiling Lv 1 1,345
  8. Avatar for BootsMcGraw 8. BootsMcGraw Lv 1 1,228
  9. Avatar for Bletchley Park 9. Bletchley Park Lv 1 1,218
  10. Avatar for Galaxie 10. Galaxie Lv 1 1,163

Recent small molecule design puzzles

Puzzle Status
2739: LRH-1 Round 5 Open for the next 5 days
2736: SF-1 Round 4 Closed since 1 day ago
2733: LRH-1 Round 4 Closed since 9 days ago
2730: SF-1 Round 3 Closed since 16 days ago
2727: LRH-1 Round 3 Closed since 23 days ago