Small Molecule Design puzzles

CASP10 Kinect CASP ROLL Hand-Folding CASP11 Predicted Contacts Pilot Overall Beginner Novice Intermediate Advanced Design Small Molecule Design Prediction Symmetry Electron Density

Players design inhibitors or modulators for folded proteins -- no protein folding required! Create new small molecules by modifying individual atoms, adding and deleting fragments, and using reaction-based design for tractable lab testing. The number of possibilities is estimated at 10^60!

Leaderboard: top small molecule design soloists

  1. Avatar for Floddi
    1. Floddi Lv 1
    5,580
  2. Avatar for ucad 2. ucad Lv 1 5,424
  3. Avatar for gmn 3. gmn Lv 1 4,698
  4. Avatar for Bruno Kestemont 4. Bruno Kestemont Lv 1 4,398
  5. Avatar for arotomic 5. arotomic Lv 1 4,209
  6. Avatar for alcor29 6. alcor29 Lv 1 4,008
  7. Avatar for Bletchley Park 7. Bletchley Park Lv 1 3,795
  8. Avatar for LociOiling 8. LociOiling Lv 1 3,429
  9. Avatar for carxo 9. carxo Lv 1 3,222
  10. Avatar for BootsMcGraw 9. BootsMcGraw Lv 1 3,222

Recent small molecule design puzzles

Puzzle Status
2748: SF-1 Round 6 Closed since 14 days ago
2745: LRH-1 Round 6 Closed since 18 days ago