Small Molecule Design puzzles

CASP10 Kinect CASP ROLL Hand-Folding CASP11 Predicted Contacts Pilot Overall Beginner Novice Intermediate Advanced Design Small Molecule Design Prediction Symmetry Electron Density

Players design inhibitors or modulators for folded proteins -- no protein folding required! Create new small molecules by modifying individual atoms, adding and deleting fragments, and using reaction-based design for tractable lab testing. The number of possibilities is estimated at 10^60!

Leaderboard: top small molecule design soloists

  1. Avatar for JarJarBinks 191. JarJarBinks Lv 1 1
  2. Avatar for Peevenpooberry 191. Peevenpooberry Lv 1 1
  3. Avatar for machilde1 191. machilde1 Lv 1 1
  4. Avatar for JDewyer 191. JDewyer Lv 1 1
  5. Avatar for Kitty-Yang 191. Kitty-Yang Lv 1 1
  6. Avatar for fikret 191. fikret Lv 1 1
  7. Avatar for SounaLaMwuad 191. SounaLaMwuad Lv 1 1
  8. Avatar for symbiote2022 191. symbiote2022 Lv 1 1
  9. Avatar for LilianDev 191. LilianDev Lv 1 1
  10. Avatar for AJ87 191. AJ87 Lv 1 1

Recent small molecule design puzzles

Puzzle Status
2748: SF-1 Round 6 Closed since 4 days ago
2745: LRH-1 Round 6 Closed since 8 days ago
2742: SF-1 Round 5 Closed since 18 days ago