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998: 80 Residue Monomer Design: SS Design

Closed since over 11 years ago

Intermediate Intermediate Overall Overall Design Design

Summary

Created: October 15, 2014
Expires: October 21, 2014 at 19:00 UTC
Max points: 100

Description

In natural proteins, different amino acids show different propensities for forming secondary structures like alpha helices and beta strands. This puzzle includes a new SS Design filter that restricts the use of GLY residues in helices and sheets. There are several other filters in effect; see the puzzle comments for details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!