Design puzzles

CASP10 Kinect CASP ROLL Hand-Folding CASP11 Predicted Contacts Pilot Overall Beginner Novice Intermediate Advanced Design Small Molecule Design Prediction Symmetry Electron Density

In this category, players design new proteins for anything and everything -- from eco-friendly materials, to treatments for deadly diseases, to super-efficient enzymes. Players must design their protein so that it achieves the puzzle Objectives, and change its sequence so that the protein folds correctly.

Leaderboard: top design soloists

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Recent design puzzles

Puzzle Status
Design of the Month: March 2023 Closed since about 3 years ago
Design of the Month: February 2023 Closed since about 3 years ago