Placeholder image of a protein
Icon representing a puzzle

1076: Vancomycin Binder Design

Closed since almost 11 years ago

Intermediate Overall Design

Summary

Created
April 16, 2015
Expires
Max points
100
Description

Design a binding pocket for vancomycin! Scientists in the Baker Lab are trying to design proteins that can bind vancomycin and upon binding generate a signal. With this technology it would be possible to test patients that have been treated with antibiotics if they still have small amounts left before they leave e.g. a hospital. The aim of this puzzle is to optimize the interaction between a protein and the small molecule vancomycin. This puzzle has four different starting structures, all with slightly different residues at the binding site; resetting the puzzle will cycle through the different models.

Top groups

  1. Avatar for Minions of TWIS 21. Minions of TWIS 1 pt. 9,056
  2. Avatar for Deleted group 22. Deleted group pts. 9,056
  3. Avatar for Czech National Team 23. Czech National Team 1 pt. 8,832
  4. Avatar for DSN @ Home 24. DSN @ Home 1 pt. 8,757
  5. Avatar for Window Group 25. Window Group 1 pt. 7,762
  1. Avatar for YeshuaLives 41. YeshuaLives Lv 1 43 pts. 9,535
  2. Avatar for egran48 42. egran48 Lv 1 42 pts. 9,532
  3. Avatar for nemo7731 43. nemo7731 Lv 1 41 pts. 9,530
  4. Avatar for crpainter 44. crpainter Lv 1 40 pts. 9,528
  5. Avatar for cobaltteal 45. cobaltteal Lv 1 39 pts. 9,526
  6. Avatar for bertro 46. bertro Lv 1 38 pts. 9,521
  7. Avatar for joremen 47. joremen Lv 1 37 pts. 9,520
  8. Avatar for Blipperman 48. Blipperman Lv 1 36 pts. 9,516
  9. Avatar for dcrwheeler 49. dcrwheeler Lv 1 35 pts. 9,510
  10. Avatar for Bushman 50. Bushman Lv 1 34 pts. 9,508

Comments