Placeholder image of a protein
Icon representing a puzzle

1076: Vancomycin Binder Design

Closed since almost 11 years ago

Intermediate Overall Design

Summary

Created
April 16, 2015
Expires
Max points
100
Description

Design a binding pocket for vancomycin! Scientists in the Baker Lab are trying to design proteins that can bind vancomycin and upon binding generate a signal. With this technology it would be possible to test patients that have been treated with antibiotics if they still have small amounts left before they leave e.g. a hospital. The aim of this puzzle is to optimize the interaction between a protein and the small molecule vancomycin. This puzzle has four different starting structures, all with slightly different residues at the binding site; resetting the puzzle will cycle through the different models.

Top groups

  1. Avatar for Minions of TWIS 21. Minions of TWIS 1 pt. 9,056
  2. Avatar for Deleted group 22. Deleted group pts. 9,056
  3. Avatar for Czech National Team 23. Czech National Team 1 pt. 8,832
  4. Avatar for DSN @ Home 24. DSN @ Home 1 pt. 8,757
  5. Avatar for Window Group 25. Window Group 1 pt. 7,762
  1. Avatar for SKSbell 71. SKSbell Lv 1 20 pts. 9,456
  2. Avatar for erikviking 72. erikviking Lv 1 20 pts. 9,454
  3. Avatar for fishercat 73. fishercat Lv 1 19 pts. 9,445
  4. Avatar for Crossed Sticks 74. Crossed Sticks Lv 1 19 pts. 9,441
  5. Avatar for KarenCH 75. KarenCH Lv 1 18 pts. 9,429
  6. Avatar for Grom 76. Grom Lv 1 18 pts. 9,428
  7. Avatar for TomTaylor 77. TomTaylor Lv 1 17 pts. 9,425
  8. Avatar for alcor29 78. alcor29 Lv 1 17 pts. 9,416
  9. Avatar for smholst 79. smholst Lv 1 16 pts. 9,407
  10. Avatar for JUMELLE54 80. JUMELLE54 Lv 1 16 pts. 9,406

Comments