Foldit

1125: 60 Residue Monomer Design

Closed since over 10 years ago

Summary

Created: August 12, 2015
Expires: August 19, 2015 at 23:00 UTC
Max points: 100

Description

This is a small 60 residue design puzzle. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

11. Deleted group pts. 9,533
12. freefolder 2 pts. 9,277
13. FoldIt@Netherlands 2 pts. 8,921
14. BOINC@Poland 1 pt. 8,686
15. CureCoin 1 pt. 7,926
16. xkcd 1 pt. 7,506
17. Piratenpartei Deutschland 1 pt. 6,949
18. Natural Abilities 1 pt. 5,874
19. ROMANIA Team 1 pt. 5,527
20. DSN @ Home 1 pt. 4,150

31. Glen B Lv 1 48 pts. 9,855
32. pvc78 Lv 1 47 pts. 9,850
33. stomjoh Lv 1 46 pts. 9,848
34. goastano Lv 1 45 pts. 9,844
35. crpainter Lv 1 44 pts. 9,842
36. christioanchauvin Lv 1 42 pts. 9,842
37. Vredeman Lv 1 41 pts. 9,838
38. gitwut Lv 1 40 pts. 9,831
39. TomTaylor Lv 1 39 pts. 9,830
40. Anfinsen_slept_here Lv 1 38 pts. 9,825

Comments

bkoep Staff Lv 1

August 12, 2015

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 25% of the residues are buried in the core of your design.

Fragment Score: Scans for parts of your design that are unlikely to fold up naturally. Use Rebuild and Remix tools to fix these regions of your design!

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.