Placeholder image of a protein
Icon representing a puzzle

1191: 65 Residue Symmetric Tetramer: H-Bond Networks

Closed since about 10 years ago

Intermediate Overall Design Symmetry

Summary

Created
February 07, 2016
Expires
Max points
100
Description

This symmetric design puzzle has C4 symmetry, with four symmetric chains. The Hbond Network Filter encourages players to bury satisfied Hbond networks at the interface, but note that no more than six inter-molecular Hbonds may contribute to the filter! There are several other filters in effect; see the puzzle comments for details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for Beta Folders
    1. Beta Folders
    100 pts. 13,269
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 78 pts. 13,264
  3. Avatar for Contenders 3. Contenders 60 pts. 13,246
  4. Avatar for Go Science 4. Go Science 45 pts. 13,024
  5. Avatar for Deleted group 5. Deleted group pts. 13,015
  6. Avatar for Void Crushers 6. Void Crushers 24 pts. 12,851
  7. Avatar for Gargleblasters 7. Gargleblasters 17 pts. 12,842
  8. Avatar for L'Alliance Francophone 8. L'Alliance Francophone 12 pts. 12,817
  9. Avatar for HMT heritage 9. HMT heritage 8 pts. 12,451
  10. Avatar for Italiani Al Lavoro 10. Italiani Al Lavoro 6 pts. 12,124
  1. Avatar for pmdpmd 41. pmdpmd Lv 1 31 pts. 12,500
  2. Avatar for Scopper 42. Scopper Lv 1 30 pts. 12,492
  3. Avatar for Museka 43. Museka Lv 1 29 pts. 12,490
  4. Avatar for WBarme1234 44. WBarme1234 Lv 1 28 pts. 12,444
  5. Avatar for smilingone 45. smilingone Lv 1 27 pts. 12,387
  6. Avatar for Anfinsen_slept_here 46. Anfinsen_slept_here Lv 1 26 pts. 12,346
  7. Avatar for phi16 47. phi16 Lv 1 26 pts. 12,346
  8. Avatar for crpainter 48. crpainter Lv 1 25 pts. 12,264
  9. Avatar for stomjoh 49. stomjoh Lv 1 24 pts. 12,201
  10. Avatar for Vinara 50. Vinara Lv 1 23 pts. 12,164

Comments

bkoep Staff Lv 1

seems this config. lends itself to serine bonding to each other. had other types bonded early but scripts changed them, wondering if this is just a glitch or its an OK arrangement.

retiredmichael Lv 1

Just curious.. is it posible to get a puzzle with tetragonal simmetry instead of c4? not all the starting pieces on the same plane and making a Regular Tetrahedron

In order to get a more 3d / globular and non-parallel piece?

martin.szew Lv 1

Just curious.. is it posible to get a puzzle with tetragonal simmetry instead of c4? not all the starting pieces on the same plane and making a Regular Tetrahedron

In order to get a more 3d / globular and non-parallel piece?