Placeholder image of a protein
Icon representing a puzzle

1207: Revisiting Puzzle 142: Rosetta Decoy 6

Closed since about 10 years ago

Intermediate Overall Prediction

Summary

Created
March 15, 2016
Expires
Max points
100
Description

This is a throwback puzzle to the early days of Foldit. This protein was evolved in vitro to bind testosterone; the starting structure is a model produced by Rosetta. This protein contains two cysteine residues, which oxidize to form a single disulfide bond. We are revisiting old Foldit puzzles so we can see how useful the recent additions to the game have been.



Sequence:


AAPTATVTPSSGLSDGTVVKVAGAGLQAGTAYWVAQWARVDTGVWAYNPADNSSVTADANGSASTSLTVRRSFEGFLFDGTRWGTVDCTTAACQVGLSDAAGNGPEGVAISF

Top groups

  1. Avatar for DSN @ Home 21. DSN @ Home 1 pt. 9,218
  2. Avatar for Deleted group 22. Deleted group pts. 9,153
  3. Avatar for Newbs to Experts 23. Newbs to Experts 1 pt. 9,144
  4. Avatar for Rechenkraft.net 24. Rechenkraft.net 1 pt. 9,054
  5. Avatar for Window Group 25. Window Group 1 pt. 8,683
  1. Avatar for smholst 31. smholst Lv 1 47 pts. 10,015
  2. Avatar for actiasluna 32. actiasluna Lv 1 46 pts. 10,000
  3. Avatar for Bushman 33. Bushman Lv 1 44 pts. 9,993
  4. Avatar for Grom 34. Grom Lv 1 43 pts. 9,985
  5. Avatar for retiredmichael 35. retiredmichael Lv 1 42 pts. 9,983
  6. Avatar for O Seki To 36. O Seki To Lv 1 41 pts. 9,982
  7. Avatar for grogar7 37. grogar7 Lv 1 40 pts. 9,981
  8. Avatar for Deleted player 38. Deleted player pts. 9,980
  9. Avatar for jobo0502 39. jobo0502 Lv 1 38 pts. 9,978
  10. Avatar for joremen 40. joremen Lv 1 36 pts. 9,977

Comments

Timo van der Laan Lv 1

With all the crashing, I am not able to do this puzzle right.
Currently in top 10 but I am sure I would get at least 100 pts more if I could run all scripts without crashing

O Seki To Lv 1

the puzzle constantly crashing. The top was 15 minutes continuous running time. Initially I thought the problem was with my computer, but it seems others have the same difficulties.

It would be great suspending this puzzle till the crashing bug eliminated…

grogar7 Lv 1

This puzzle should be suspended or deprecated. Those (like my team mate Galaxie) who have not accepted the update to main, are able to run this puzzle unimpeded. Those who did accept the update are crashing regularly on 1207. Seems unfair!

actiasluna Lv 1

FYI - I'm running from a freshly installed (not updated to an existing) application running the updated Main and 1207 is stable for me. It's worth the time to do! Just be sure you save your active puzzles and share them with yourself, and save the options.txt and all.macro files (your recipes and settings) from the old version before ditching the old application and reinstalling.

(This is particularly important to do periodically on the Mac platform, in which Foldit gets "foldit bloat" - the application grows over time and things slow down.)