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1211: 85 Residue Monomer Design: Rama Map

Closed since about 10 years ago

Intermediate Overall Design

Summary

Created
March 25, 2016
Expires
Max points
100
Description

This is another basic design puzzle for players to practice with the Rama Map. The Rama map can be accessed from the Actions tab (Original Interface) or the Main menu (Selection Interface). See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for Deleted group 11. Deleted group pts. 9,671
  2. Avatar for BOINC@Poland 12. BOINC@Poland 3 pts. 9,628
  3. Avatar for Deleted group 13. Deleted group pts. 8,492
  4. Avatar for Rechenkraft.net 14. Rechenkraft.net 1 pt. 7,985
  5. Avatar for DSN @ Home 15. DSN @ Home 1 pt. 7,352
  6. Avatar for foldeRNA 16. foldeRNA 1 pt. 4,891
  7. Avatar for Natural Abilities 17. Natural Abilities 1 pt. 4,428
  8. Avatar for Team South Africa 18. Team South Africa 1 pt. 0
  9. Avatar for Russian team 19. Russian team 1 pt. 0
  10. Avatar for xkcd 20. xkcd 1 pt. 0
  1. Avatar for guineapig 91. guineapig Lv 1 6 pts. 9,593
  2. Avatar for ViJay7019 92. ViJay7019 Lv 1 6 pts. 9,575
  3. Avatar for pfirth 93. pfirth Lv 1 5 pts. 9,562
  4. Avatar for Merf 94. Merf Lv 1 5 pts. 9,515
  5. Avatar for navn 95. navn Lv 1 5 pts. 9,464
  6. Avatar for uihcv 96. uihcv Lv 1 5 pts. 9,421
  7. Avatar for Tac1 97. Tac1 Lv 1 5 pts. 9,394
  8. Avatar for arginia 98. arginia Lv 1 4 pts. 9,377
  9. Avatar for hada 99. hada Lv 1 4 pts. 9,372
  10. Avatar for parsnip 100. parsnip Lv 1 4 pts. 9,348

Comments

bkoep Staff Lv 1

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.