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1211: 85 Residue Monomer Design: Rama Map

Closed since almost 10 years ago

Intermediate Overall Design

Summary

Created: March 25, 2016
Expires: March 31, 2016 at 23:00 UTC
Max points: 100

Description

This is another basic design puzzle for players to practice with the Rama Map. The Rama map can be accessed from the Actions tab (Original Interface) or the Main menu (Selection Interface). See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

11. Deleted group pts. 9,671
12. BOINC@Poland 3 pts. 9,628
13. Deleted group pts. 8,492
14. Rechenkraft.net 1 pt. 7,985
15. DSN @ Home 1 pt. 7,352
16. foldeRNA 1 pt. 4,891
17. Natural Abilities 1 pt. 4,428
18. Team South Africa 1 pt. 0
19. Russian team 1 pt. 0
20. xkcd 1 pt. 0

11. reefyrob Lv 1 78 pts. 10,569
12. nicobul Lv 1 76 pts. 10,558
13. Galaxie Lv 1 74 pts. 10,557
14. Susume Lv 1 72 pts. 10,534
15. Bruno Kestemont Lv 1 71 pts. 10,525
16. spvincent Lv 1 69 pts. 10,523
17. bertro Lv 1 67 pts. 10,522
18. gloverd Lv 1 65 pts. 10,511
19. hpaege Lv 1 64 pts. 10,507
20. stomjoh Lv 1 62 pts. 10,503

Comments

bkoep Staff Lv 1

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.