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1211: 85 Residue Monomer Design: Rama Map

Closed since almost 10 years ago

Intermediate Overall Design

Summary

Created
March 25, 2016
Expires
Max points
100
Description

This is another basic design puzzle for players to practice with the Rama Map. The Rama map can be accessed from the Actions tab (Original Interface) or the Main menu (Selection Interface). See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

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  6. Avatar for foldeRNA 16. foldeRNA 1 pt. 4,891
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  8. Avatar for Team South Africa 18. Team South Africa 1 pt. 0
  9. Avatar for Russian team 19. Russian team 1 pt. 0
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  4. Avatar for fiendish_ghoul 34. fiendish_ghoul Lv 1 42 pts. 10,395
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  8. Avatar for Blipperman 38. Blipperman Lv 1 37 pts. 10,356
  9. Avatar for O Seki To 39. O Seki To Lv 1 36 pts. 10,354
  10. Avatar for Anfinsen_slept_here 40. Anfinsen_slept_here Lv 1 35 pts. 10,337

Comments

bkoep Staff Lv 1

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.