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1211: 85 Residue Monomer Design: Rama Map

Closed since about 10 years ago

Intermediate Overall Design

Summary

Created
March 25, 2016
Expires
Max points
100
Description

This is another basic design puzzle for players to practice with the Rama Map. The Rama map can be accessed from the Actions tab (Original Interface) or the Main menu (Selection Interface). See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for SETI.Germany 21. SETI.Germany 1 pt. 0
  2. Avatar for Window Group 22. Window Group 1 pt. 0
  1. Avatar for Franco Padelletti 61. Franco Padelletti Lv 1 18 pts. 10,110
  2. Avatar for deLaCeiba 62. deLaCeiba Lv 1 17 pts. 10,058
  3. Avatar for alcor29 63. alcor29 Lv 1 17 pts. 10,030
  4. Avatar for dbuske 64. dbuske Lv 1 16 pts. 10,011
  5. Avatar for drumpeter18yrs9yrs 65. drumpeter18yrs9yrs Lv 1 16 pts. 10,003
  6. Avatar for pmthomson90 66. pmthomson90 Lv 1 15 pts. 9,984
  7. Avatar for lynnai 67. lynnai Lv 1 15 pts. 9,981
  8. Avatar for georg137 68. georg137 Lv 1 14 pts. 9,965
  9. Avatar for Bautho 69. Bautho Lv 1 14 pts. 9,956
  10. Avatar for weitzen 70. weitzen Lv 1 13 pts. 9,945

Comments

bkoep Staff Lv 1

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.