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1211: 85 Residue Monomer Design: Rama Map

Closed since almost 10 years ago

Intermediate Overall Design

Summary

Created: March 25, 2016
Expires: March 31, 2016 at 23:00 UTC
Max points: 100

Description

This is another basic design puzzle for players to practice with the Rama Map. The Rama map can be accessed from the Actions tab (Original Interface) or the Main menu (Selection Interface). See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

1. Contenders
100 pts. 10,672
2. Go Science 79 pts. 10,658
3. Beta Folders 61 pts. 10,647
4. Anthropic Dreams 47 pts. 10,647
5. L'Alliance Francophone 35 pts. 10,558
6. Gargleblasters 26 pts. 10,554
7. Void Crushers 19 pts. 10,493
8. HMT heritage 14 pts. 10,398
9. Deleted group pts. 10,337
10. Italiani Al Lavoro 7 pts. 10,153

11. gloverd Lv 1 22 pts. 10,651
12. smilingone Lv 1 19 pts. 10,647
13. Deleted player pts. 10,646
14. LociOiling Lv 1 13 pts. 10,645
15. packer Lv 1 11 pts. 10,630
16. reefyrob Lv 1 9 pts. 10,628
17. penteplayer Lv 1 7 pts. 10,628
18. Galaxie Lv 1 6 pts. 10,627
19. retiredmichael Lv 1 5 pts. 10,626
20. TomTaylor Lv 1 4 pts. 10,617

Comments

bkoep Staff Lv 1

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.