1211: 85 Residue Monomer Design: Rama Map

Closed since almost 10 years ago

Summary

• Created: March 25, 2016
• Expires: March 31, 2016 at 23:00 UTC
• Max points: 100

Description

This is another basic design puzzle for players to practice with the Rama Map. The Rama map can be accessed from the Actions tab (Original Interface) or the Main menu (Selection Interface). See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

• 1. Contenders 100 pts. 10,672
• 2. Go Science 79 pts. 10,658
• 3. Beta Folders 61 pts. 10,647
• 4. Anthropic Dreams 47 pts. 10,647
• 5. L'Alliance Francophone 35 pts. 10,558
• 6. Gargleblasters 26 pts. 10,554
• 7. Void Crushers 19 pts. 10,493
• 8. HMT heritage 14 pts. 10,398
• 9. Deleted group pts. 10,337
• 10. Italiani Al Lavoro 7 pts. 10,153

Top soloists

• 101. bwkittitas 4 pts. 9,331
• 102. Close At Hand 4 pts. 9,279
• 103. sean4046 4 pts. 9,237
• 104. andrewxc 3 pts. 9,226
• 105. hansvandenhof 3 pts. 9,193
• 106. NotJim99 3 pts. 9,121
• 107. Wheeler22 3 pts. 9,101
• 108. Cerzax 3 pts. 9,065
• 109. JUMELLE54 3 pts. 8,978
• 110. rinze 3 pts. 8,907

Comments

[bkoep]

Residue IE Score: Monitors that all PHE, TYR, and TRP residues are scoring well.

Core Existence: Ensures that at least 30% of the residues are buried in the core of your design.

Secondary Structure: Checks that no more than 50% of residues are in helices; penalties are incurred if more than 50% of residues form helices.

Secondary Structure Design: Penalizes all CYS residues. Penalizes GLY, ALA, and PRO residues in helices and sheets.