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1424: Extra Large Monomer Design

Closed since over 8 years ago

Intermediate Overall Design

Summary

Created
September 01, 2017
Expires
Max points
100
Description

This puzzle challenges players to design a single-chain protein with 95-120 residues. We've adjusted the scoring function here so that alanine residues are more tolerable in loops (they are still restricted in helices and sheets!). The starting structure has 95 residues, but more can be added at a cost of 23 points per residue. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for CureCoin 11. CureCoin 1 pt. 6,596
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  4. Avatar for DSN @ Home 14. DSN @ Home 1 pt. 385
  5. Avatar for xkcd 15. xkcd 1 pt. 0
  1. Avatar for Susume 21. Susume Lv 1 44 pts. 10,510
  2. Avatar for reefyrob 22. reefyrob Lv 1 42 pts. 10,494
  3. Avatar for phi16 23. phi16 Lv 1 40 pts. 10,491
  4. Avatar for pvc78 24. pvc78 Lv 1 38 pts. 10,428
  5. Avatar for Blipperman 25. Blipperman Lv 1 37 pts. 10,277
  6. Avatar for Bautho 26. Bautho Lv 1 35 pts. 10,266
  7. Avatar for toshiue 27. toshiue Lv 1 33 pts. 10,245
  8. Avatar for georg137 28. georg137 Lv 1 32 pts. 10,234
  9. Avatar for gmn 29. gmn Lv 1 30 pts. 10,218
  10. Avatar for mimi 30. mimi Lv 1 29 pts. 10,214

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