Placeholder image of a protein
Icon representing a puzzle

1424: Extra Large Monomer Design

Closed since over 8 years ago

Intermediate Overall Design

Summary

Created
September 01, 2017
Expires
Max points
100
Description

This puzzle challenges players to design a single-chain protein with 95-120 residues. We've adjusted the scoring function here so that alanine residues are more tolerable in loops (they are still restricted in helices and sheets!). The starting structure has 95 residues, but more can be added at a cost of 23 points per residue. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for CureCoin 11. CureCoin 1 pt. 6,596
  2. Avatar for Natural Abilities 12. Natural Abilities 1 pt. 3,775
  3. Avatar for St Pat's Biology 203 13. St Pat's Biology 203 1 pt. 469
  4. Avatar for DSN @ Home 14. DSN @ Home 1 pt. 385
  5. Avatar for xkcd 15. xkcd 1 pt. 0
  1. Avatar for Festering Wounds 51. Festering Wounds Lv 1 9 pts. 8,984
  2. Avatar for andrewxc 52. andrewxc Lv 1 9 pts. 8,958
  3. Avatar for Atrus_Homeboy 53. Atrus_Homeboy Lv 1 8 pts. 8,697
  4. Avatar for pfirth 54. pfirth Lv 1 8 pts. 8,692
  5. Avatar for SKSbell 55. SKSbell Lv 1 7 pts. 8,689
  6. Avatar for rinze 56. rinze Lv 1 7 pts. 8,449
  7. Avatar for Merf 57. Merf Lv 1 6 pts. 8,447
  8. Avatar for harvardman 58. harvardman Lv 1 6 pts. 8,371
  9. Avatar for diamonddays 59. diamonddays Lv 1 6 pts. 8,365
  10. Avatar for SNix 60. SNix Lv 1 5 pts. 8,305

Comments