Placeholder image of a protein
Icon representing a puzzle

1424: Extra Large Monomer Design

Closed since over 8 years ago

Intermediate Overall Design

Summary

Created
September 01, 2017
Expires
Max points
100
Description

This puzzle challenges players to design a single-chain protein with 95-120 residues. We've adjusted the scoring function here so that alanine residues are more tolerable in loops (they are still restricted in helices and sheets!). The starting structure has 95 residues, but more can be added at a cost of 23 points per residue. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for Gargleblasters
    1. Gargleblasters
    100 pts. 11,040
  2. Avatar for Beta Folders 2. Beta Folders 70 pts. 10,991
  3. Avatar for Anthropic Dreams 3. Anthropic Dreams 47 pts. 10,972
  4. Avatar for Contenders 4. Contenders 30 pts. 10,828
  5. Avatar for Go Science 5. Go Science 19 pts. 10,783
  6. Avatar for Marvin's bunch 6. Marvin's bunch 11 pts. 10,758
  7. Avatar for Void Crushers 7. Void Crushers 7 pts. 10,570
  8. Avatar for Deleted group 8. Deleted group pts. 9,915
  9. Avatar for L'Alliance Francophone 9. L'Alliance Francophone 2 pts. 9,753
  10. Avatar for Kotocycle 10. Kotocycle 1 pt. 9,446
  1. Avatar for eromana
    1. eromana Lv 1
    100 pts. 11,040
  2. Avatar for actiasluna 2. actiasluna Lv 1 82 pts. 11,039
  3. Avatar for andrewxc 3. andrewxc Lv 1 66 pts. 11,035
  4. Avatar for Skippysk8s 4. Skippysk8s Lv 1 53 pts. 11,034
  5. Avatar for Enzyme 5. Enzyme Lv 1 42 pts. 11,033
  6. Avatar for smilingone 6. smilingone Lv 1 33 pts. 10,991
  7. Avatar for LociOiling 7. LociOiling Lv 1 26 pts. 10,991
  8. Avatar for bertro 8. bertro Lv 1 20 pts. 10,989
  9. Avatar for reefyrob 9. reefyrob Lv 1 15 pts. 10,987
  10. Avatar for retiredmichael 10. retiredmichael Lv 1 11 pts. 10,979

Comments