Placeholder image of a protein
Icon representing a puzzle

1424: Extra Large Monomer Design

Closed since over 8 years ago

Intermediate Overall Design

Summary

Created
September 01, 2017
Expires
Max points
100
Description

This puzzle challenges players to design a single-chain protein with 95-120 residues. We've adjusted the scoring function here so that alanine residues are more tolerable in loops (they are still restricted in helices and sheets!). The starting structure has 95 residues, but more can be added at a cost of 23 points per residue. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for Gargleblasters
    1. Gargleblasters
    100 pts. 11,040
  2. Avatar for Beta Folders 2. Beta Folders 70 pts. 10,991
  3. Avatar for Anthropic Dreams 3. Anthropic Dreams 47 pts. 10,972
  4. Avatar for Contenders 4. Contenders 30 pts. 10,828
  5. Avatar for Go Science 5. Go Science 19 pts. 10,783
  6. Avatar for Marvin's bunch 6. Marvin's bunch 11 pts. 10,758
  7. Avatar for Void Crushers 7. Void Crushers 7 pts. 10,570
  8. Avatar for Deleted group 8. Deleted group pts. 9,915
  9. Avatar for L'Alliance Francophone 9. L'Alliance Francophone 2 pts. 9,753
  10. Avatar for Kotocycle 10. Kotocycle 1 pt. 9,446
  1. Avatar for eromana 111. eromana Lv 1 1 pt. 0
  2. Avatar for Hollinas 112. Hollinas Lv 1 1 pt. 0
  3. Avatar for bertro 113. bertro Lv 1 1 pt. 0
  4. Avatar for bcre8tvv 114. bcre8tvv Lv 1 1 pt. 0
  5. Avatar for jausmh 115. jausmh Lv 1 1 pt. 0
  6. Avatar for multaq 116. multaq Lv 1 1 pt. 0
  7. Avatar for px43 117. px43 Lv 1 1 pt. 0
  8. Avatar for pauldunn 118. pauldunn Lv 1 1 pt. 0
  9. Avatar for cas0362 119. cas0362 Lv 1 1 pt. 0
  10. Avatar for Jaco van As 120. Jaco van As Lv 1 1 pt. 0

Comments