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1424: Extra Large Monomer Design

Closed since over 8 years ago

Intermediate Overall Design

Summary

Created
September 01, 2017
Expires
Max points
100
Description

This puzzle challenges players to design a single-chain protein with 95-120 residues. We've adjusted the scoring function here so that alanine residues are more tolerable in loops (they are still restricted in helices and sheets!). The starting structure has 95 residues, but more can be added at a cost of 23 points per residue. See the puzzle comments for filter details. The Baker Lab will run folding predictions on your solutions for this puzzle, and those that perform well will be synthesized in the lab. Remember, you can use the Upload for Scientists button for up to 5 designs that you want us to look at, even if they are not the best-scoring solutions!

Top groups

  1. Avatar for Gargleblasters
    1. Gargleblasters
    100 pts. 11,040
  2. Avatar for Beta Folders 2. Beta Folders 70 pts. 10,991
  3. Avatar for Anthropic Dreams 3. Anthropic Dreams 47 pts. 10,972
  4. Avatar for Contenders 4. Contenders 30 pts. 10,828
  5. Avatar for Go Science 5. Go Science 19 pts. 10,783
  6. Avatar for Marvin's bunch 6. Marvin's bunch 11 pts. 10,758
  7. Avatar for Void Crushers 7. Void Crushers 7 pts. 10,570
  8. Avatar for Deleted group 8. Deleted group pts. 9,915
  9. Avatar for L'Alliance Francophone 9. L'Alliance Francophone 2 pts. 9,753
  10. Avatar for Kotocycle 10. Kotocycle 1 pt. 9,446
  1. Avatar for Bruno Kestemont 31. Bruno Kestemont Lv 1 27 pts. 10,177
  2. Avatar for fishercat 32. fishercat Lv 1 26 pts. 10,047
  3. Avatar for drumpeter18yrs9yrs 33. drumpeter18yrs9yrs Lv 1 25 pts. 9,915
  4. Avatar for smilingone 34. smilingone Lv 1 24 pts. 9,884
  5. Avatar for christioanchauvin 35. christioanchauvin Lv 1 22 pts. 9,753
  6. Avatar for Deleted player 36. Deleted player pts. 9,751
  7. Avatar for jamiexq 37. jamiexq Lv 1 20 pts. 9,664
  8. Avatar for Anton Trikshev 38. Anton Trikshev Lv 1 19 pts. 9,660
  9. Avatar for Mike Cassidy 39. Mike Cassidy Lv 1 18 pts. 9,637
  10. Avatar for cinnamonkitty 40. cinnamonkitty Lv 1 17 pts. 9,519

Comments