1598: Cryo-EM Freestyle with Density

Closed since over 7 years ago

Summary

• Created: November 12, 2018
• Expires: November 27, 2018 at 14:00 UTC
• Max points: 100

Description

This protein is another part of the same protein complex with multiple subunits from Puzzle 1554 and Puzzle 1588, which has been the target of cryo-EM experiments. We are giving you an extended chain to start with, so good luck!

Top groups

• 1. Anthropic Dreams 100 pts. 18,575
• 2. Beta Folders 76 pts. 18,531
• 3. Go Science 56 pts. 18,377
• 4. Marvin's bunch 41 pts. 18,306
• 5. Gargleblasters 29 pts. 15,926
• 6. Void Crushers 20 pts. 14,746
• 7. Contenders 14 pts. 13,372
• 8. L'Alliance Francophone 9 pts. 12,343
• 9. Russian team 6 pts. 12,185
• 10. Deleted group pts. 11,046

Top soloists

• 31. christioanchauvin 39 pts. 12,092
• 32. NinjaGreg 38 pts. 11,957
• 33. georg137 36 pts. 11,905
• 34. Vinara 35 pts. 11,879
• 35. Blipperman 34 pts. 11,823
• 36. johnmitch 33 pts. 11,808
• 37. Psych0Active 32 pts. 11,781
• 38. fpc 31 pts. 11,676
• 39. smilingone 29 pts. 11,655
• 40. Skippysk8s 28 pts. 11,425

Comments

[jeff101]

I think this puzzle starts with all loops as
its secondary structure. Is that intentional?

[Bruno Kestemont]

LLLLLLLLEEEEEEELLLLLLLLEEEEEEEELLLEEEEEEEEEELLLLLEEEELLLLLLLLLEEEEEEELLLL
HHHHHHHHHHLLLLEEEEEEEEEEELLLLLEEEEEEELLEEEEEEEELLLLLLLLEEEEEEEEEEEELEEEEEEEL

copy-paste it in note 19 then run:
https://fold.it/portal/recipe/49556

(and run this recipe every time you want to recover it)

Source for prediction (it takes 30 minutes):
http://bioinf.cs.ucl.ac.uk/psipred/

[Bruno Kestemont]

However, PSIPRED prediction (bellow) is quite useful to help to fit into the density somewhere (but the density gives a quite different pattern after all)

[Vinara]

Thank you. Quick question for Foldit for Dummies: Where do I find note 19?

[jeff101]

In Puzzle 1598, if you are in the Original Interface using
the Rainbow color scheme, you can find Note 19 by Tabbing
on the blue end of the protein. A window called "Segment
Information" will appear for the segment you Tabbed on.
You can then use the left or right arrow key to move to
the "Segment Information" window for Isoleucine 19. At the
bottom of this window is a section called "Notes". You can
paste the desired secondary structure (listed above) in the
"Notes" section. The little trash can next to the "Notes"
section clears this section's contents.

[Vinara]

Thank you. :)

[toshiue]

…or you can use SS Edit 1.2 (recipe 102273)

[Bruno Kestemont]

Or AA Copy-Paste Compare