Placeholder image of a protein
Icon representing a puzzle

1775: Poly-Proline Helix Design: Round 4

Closed since over 6 years ago

Intermediate Overall Design

Summary


Created
December 19, 2019
Expires
Max points
100
Description

This is the fourth puzzle in the poly-proline helix design series! The starting structure is identical to the one in round 3, with an 80 residue protein and an 8 residue helix. The backbone will be frozen to maintain the poly-proline helix secondary structure, but we are now giving you free rein to design the residues on the helix. We want to see how you will satisfy the exposed oxygens on the helix backbone, because proteins that satisfy all internal oxygens with hydrogen bonds have the best chance of folding in the lab.
Happy folding!

Top groups


  1. Avatar for FoldIt@Netherlands 11. FoldIt@Netherlands 1 pt. 10,343
  2. Avatar for Team New Zealand 12. Team New Zealand 1 pt. 10,324
  3. Avatar for Italiani Al Lavoro 14. Italiani Al Lavoro 1 pt. 9,170
  4. Avatar for Trinity Biology 15. Trinity Biology 1 pt. 8,265
  5. Avatar for Deleted group 16. Deleted group pts. 5,385

  1. Avatar for knotartist 81. knotartist Lv 1 1 pt. 8,465
  2. Avatar for alyssa_d_V2.0 82. alyssa_d_V2.0 Lv 1 1 pt. 8,265
  3. Avatar for Pisqis 83. Pisqis Lv 1 1 pt. 6,642
  4. Avatar for BogdanW3 85. BogdanW3 Lv 1 1 pt. 5,357
  5. Avatar for leannerikicheever 86. leannerikicheever Lv 1 1 pt. 4,837
  6. Avatar for Datstandin 87. Datstandin Lv 1 1 pt. 4,446
  7. Avatar for deaphroat 88. deaphroat Lv 1 1 pt. 4,446
  8. Avatar for liangsouth 89. liangsouth Lv 1 1 pt. 4,030
  9. Avatar for 01010011111 90. 01010011111 Lv 1 1 pt. 4,012

Comments


Deleted user

Residue Count (max +100)
Penalizes a residue count above 80 by 20 Foldit points per additional residue. The count is capped at 85.