Placeholder image of a protein
Icon representing a puzzle

1775: Poly-Proline Helix Design: Round 4

Closed since about 6 years ago

Intermediate Overall Design

Summary

Created
December 19, 2019
Expires
Max points
100
Description

This is the fourth puzzle in the poly-proline helix design series! The starting structure is identical to the one in round 3, with an 80 residue protein and an 8 residue helix. The backbone will be frozen to maintain the poly-proline helix secondary structure, but we are now giving you free rein to design the residues on the helix. We want to see how you will satisfy the exposed oxygens on the helix backbone, because proteins that satisfy all internal oxygens with hydrogen bonds have the best chance of folding in the lab.
Happy folding!

Top groups

  1. Avatar for Gargleblasters
    1. Gargleblasters
    100 pts. 11,135
  2. Avatar for Go Science 2. Go Science 71 pts. 11,110
  3. Avatar for Anthropic Dreams 3. Anthropic Dreams 49 pts. 11,082
  4. Avatar for Void Crushers 4. Void Crushers 33 pts. 11,078
  5. Avatar for Contenders 5. Contenders 22 pts. 11,015
  6. Avatar for L'Alliance Francophone 6. L'Alliance Francophone 14 pts. 10,913
  7. Avatar for Beta Folders 7. Beta Folders 8 pts. 10,811
  8. Avatar for Marvin's bunch 8. Marvin's bunch 5 pts. 10,708
  9. Avatar for HMT heritage 9. HMT heritage 3 pts. 10,707
  10. Avatar for Russian team 10. Russian team 2 pts. 10,703
  1. Avatar for Blipperman
    1. Blipperman Lv 1
    100 pts. 11,122
  2. Avatar for ManVsYard 2. ManVsYard Lv 1 81 pts. 11,118
  3. Avatar for Bruno Kestemont 3. Bruno Kestemont Lv 1 64 pts. 11,110
  4. Avatar for jeff101 4. jeff101 Lv 1 50 pts. 11,110
  5. Avatar for Skippysk8s 5. Skippysk8s Lv 1 39 pts. 11,109
  6. Avatar for NinjaGreg 6. NinjaGreg Lv 1 30 pts. 11,105
  7. Avatar for toshiue 7. toshiue Lv 1 23 pts. 11,103
  8. Avatar for silent gene 8. silent gene Lv 1 17 pts. 11,087
  9. Avatar for ZeroLeak7 9. ZeroLeak7 Lv 1 12 pts. 11,085
  10. Avatar for Galaxie 10. Galaxie Lv 1 9 pts. 11,082

Comments

Deleted user

Residue Count (max +100)
Penalizes a residue count above 80 by 20 Foldit points per additional residue. The count is capped at 85.