Placeholder image of a protein
Icon representing a puzzle

1775: Poly-Proline Helix Design: Round 4

Closed since about 6 years ago

Intermediate Overall Design

Summary

Created
December 19, 2019
Expires
Max points
100
Description

This is the fourth puzzle in the poly-proline helix design series! The starting structure is identical to the one in round 3, with an 80 residue protein and an 8 residue helix. The backbone will be frozen to maintain the poly-proline helix secondary structure, but we are now giving you free rein to design the residues on the helix. We want to see how you will satisfy the exposed oxygens on the helix backbone, because proteins that satisfy all internal oxygens with hydrogen bonds have the best chance of folding in the lab.
Happy folding!

Top groups

  1. Avatar for Gargleblasters
    1. Gargleblasters
    100 pts. 11,135
  2. Avatar for Go Science 2. Go Science 71 pts. 11,110
  3. Avatar for Anthropic Dreams 3. Anthropic Dreams 49 pts. 11,082
  4. Avatar for Void Crushers 4. Void Crushers 33 pts. 11,078
  5. Avatar for Contenders 5. Contenders 22 pts. 11,015
  6. Avatar for L'Alliance Francophone 6. L'Alliance Francophone 14 pts. 10,913
  7. Avatar for Beta Folders 7. Beta Folders 8 pts. 10,811
  8. Avatar for Marvin's bunch 8. Marvin's bunch 5 pts. 10,708
  9. Avatar for HMT heritage 9. HMT heritage 3 pts. 10,707
  10. Avatar for Russian team 10. Russian team 2 pts. 10,703
  1. Avatar for Anfinsen_slept_here 41. Anfinsen_slept_here Lv 1 8 pts. 10,502
  2. Avatar for Merf 42. Merf Lv 1 7 pts. 10,491
  3. Avatar for frood66 43. frood66 Lv 1 7 pts. 10,476
  4. Avatar for spvincent 44. spvincent Lv 1 6 pts. 10,470
  5. Avatar for fpc 45. fpc Lv 1 6 pts. 10,437
  6. Avatar for bobcat 46. bobcat Lv 1 5 pts. 10,422
  7. Avatar for alwen 47. alwen Lv 1 5 pts. 10,419
  8. Avatar for SiliconDioxide 48. SiliconDioxide Lv 1 4 pts. 10,404
  9. Avatar for alcor29 49. alcor29 Lv 1 4 pts. 10,397
  10. Avatar for Pawel Tluscik 50. Pawel Tluscik Lv 1 4 pts. 10,362

Comments

Deleted user

Residue Count (max +100)
Penalizes a residue count above 80 by 20 Foldit points per additional residue. The count is capped at 85.