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1788: Poly-Proline Helix Design: Round 7

Closed since about 6 years ago

Intermediate Overall Design

Summary

Created
January 17, 2020
Expires
Max points
100
Description

This is the seventh puzzle in the poly-proline helix design series! The starting structure is an 80 residue protein with a 5 residue helix, and all residues are mutable. The reference weight fo proline has been changed from 16.4 to 30.0 to provide a small incentive for proline usage. Keeping good hydrophobic cores with any buried polars satisfied with hydrogen bonds will help create stable structures. Hydrogen bonds are visible by selecting 'Show advanced GUI' in General Options in the Menu tab, and then selecting 'Show bonds (loop)' and 'Show bondable atoms' in the View tab.
Happy Folding!

Top groups

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Comments

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Residue Count (max +100)
Penalizes a residue count above 80 by 20 Foldit points per additional residue. The count is capped at 85.