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1791: Poly-Proline Helix Design: Round 8

Closed since about 6 years ago

Intermediate Overall Design

Summary


Created
January 24, 2020
Expires
Max points
100
Description

This is the eighth puzzle in the poly-proline helix design series! The starting structure is slightly longer than previous rounds, with a 90 residue protein and a 6 residue helix. All residues are mutable, and we have reset the proline reference energy to 16.4 to allow for a greater diversity of residues. Keeping all buried polars satisfied is still a key component of a good structure, as well as a hydrophobic core and well defined secondary structures.
Happy folding!

Top groups


  1. Avatar for Contenders 100 pts. 11,742
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 70 pts. 11,705
  3. Avatar for Go Science 3. Go Science 47 pts. 11,699
  4. Avatar for L'Alliance Francophone 4. L'Alliance Francophone 30 pts. 11,438
  5. Avatar for Gargleblasters 5. Gargleblasters 19 pts. 11,317
  6. Avatar for Beta Folders 6. Beta Folders 11 pts. 11,314
  7. Avatar for Void Crushers 7. Void Crushers 7 pts. 11,253
  8. Avatar for Marvin's bunch 8. Marvin's bunch 4 pts. 11,048
  9. Avatar for Russian team 9. Russian team 2 pts. 10,907
  10. Avatar for HMT heritage 10. HMT heritage 1 pt. 10,760

  1. Avatar for Psych0Active 91. Psych0Active Lv 1 1 pt. 6,921
  2. Avatar for pascal ochem 92. pascal ochem Lv 1 1 pt. 6,539
  3. Avatar for xythus 93. xythus Lv 1 1 pt. 5,969
  4. Avatar for frostschutz 94. frostschutz Lv 1 1 pt. 4,563
  5. Avatar for daisycurls 95. daisycurls Lv 1 1 pt. 4,547
  6. Avatar for Philippe_C 96. Philippe_C Lv 1 1 pt. 4,358
  7. Avatar for yoonthecho 97. yoonthecho Lv 1 1 pt. 4,044
  8. Avatar for sophielemur 98. sophielemur Lv 1 1 pt. 4,018
  9. Avatar for Giantbluefish 99. Giantbluefish Lv 1 1 pt. 3,890
  10. Avatar for 01010011111 100. 01010011111 Lv 1 1 pt. 3,473

Comments


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Residue Count (max +100)
Penalizes a residue count above 90 by 20 Foldit points per additional residue. The count is capped at 95.