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1791: Poly-Proline Helix Design: Round 8

Closed since about 6 years ago

Intermediate Overall Design

Summary


Created
January 24, 2020
Expires
Max points
100
Description

This is the eighth puzzle in the poly-proline helix design series! The starting structure is slightly longer than previous rounds, with a 90 residue protein and a 6 residue helix. All residues are mutable, and we have reset the proline reference energy to 16.4 to allow for a greater diversity of residues. Keeping all buried polars satisfied is still a key component of a good structure, as well as a hydrophobic core and well defined secondary structures.
Happy folding!

Top groups


  1. Avatar for Contenders 100 pts. 11,742
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 70 pts. 11,705
  3. Avatar for Go Science 3. Go Science 47 pts. 11,699
  4. Avatar for L'Alliance Francophone 4. L'Alliance Francophone 30 pts. 11,438
  5. Avatar for Gargleblasters 5. Gargleblasters 19 pts. 11,317
  6. Avatar for Beta Folders 6. Beta Folders 11 pts. 11,314
  7. Avatar for Void Crushers 7. Void Crushers 7 pts. 11,253
  8. Avatar for Marvin's bunch 8. Marvin's bunch 4 pts. 11,048
  9. Avatar for Russian team 9. Russian team 2 pts. 10,907
  10. Avatar for HMT heritage 10. HMT heritage 1 pt. 10,760

  1. Avatar for knotartist 41. knotartist Lv 1 11 pts. 10,763
  2. Avatar for O Seki To 42. O Seki To Lv 1 10 pts. 10,760
  3. Avatar for alwen 43. alwen Lv 1 9 pts. 10,736
  4. Avatar for abiogenesis 44. abiogenesis Lv 1 9 pts. 10,721
  5. Avatar for Fergersontc 45. Fergersontc Lv 1 8 pts. 10,661
  6. Avatar for aznarog 47. aznarog Lv 1 7 pts. 10,647
  7. Avatar for heather-1 48. heather-1 Lv 1 6 pts. 10,632
  8. Avatar for WBarme1234 49. WBarme1234 Lv 1 6 pts. 10,631
  9. Avatar for haabermaaster 50. haabermaaster Lv 1 6 pts. 10,607

Comments


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Residue Count (max +100)
Penalizes a residue count above 90 by 20 Foldit points per additional residue. The count is capped at 95.