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Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary


Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups


  1. Avatar for Deleted group 41. Deleted group pts. 8,693
  2. Avatar for Deleted group 44. Deleted group pts. 8,418
  3. Avatar for Team Canada 46. Team Canada 3 pts. 8,406
  4. Avatar for HMT heritage 47. HMT heritage 3 pts. 8,388
  5. Avatar for GBHS BMAH kids 48. GBHS BMAH kids 3 pts. 8,145
  6. Avatar for bmd 49. bmd 2 pts. 7,780
  7. Avatar for Titans of Biology 50. Titans of Biology 2 pts. 7,684

  1. Avatar for Dietel 741. Dietel Lv 1 4 pts. 3,687
  2. Avatar for India_friends 742. India_friends Lv 1 4 pts. 3,676
  3. Avatar for ForrestBC 743. ForrestBC Lv 1 4 pts. 3,675
  4. Avatar for Sarah___Johnson 744. Sarah___Johnson Lv 1 4 pts. 3,656
  5. Avatar for Benjamin Roeser 745. Benjamin Roeser Lv 1 4 pts. 3,597
  6. Avatar for jmdavis 746. jmdavis Lv 1 4 pts. 3,571
  7. Avatar for zbenoit 747. zbenoit Lv 1 4 pts. 3,568
  8. Avatar for zasnes 748. zasnes Lv 1 4 pts. 3,568
  9. Avatar for sed4906 749. sed4906 Lv 1 4 pts. 3,529
  10. Avatar for mei190000 750. mei190000 Lv 1 4 pts. 3,510

Comments


DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)