Placeholder image of a protein
Icon representing a puzzle

Protein Design Sandbox

Closed since about 4 years ago

Beginner

Summary

Created
March 22, 2020
Expires
Max points
100
Description

Experiment with protein design! We've disabled many of the restrictions in normal Science puzzles, so players have access to all protein designs tools, and may insert and delete any number of residues. Foldit scientists do not check the solutions from this puzzle, and playing this puzzle will not affect your global or category rankings.



Two common protein design Objectives are available, but they will not award any bonuses or penalties. The Core Existence Objective checks to see if 30% of residues are buried in the protein core, away from the water surrounding the protein. The Ideal Loops Objective looks for loops with problematic backbone folds. If you build an especially large protein, try disabling these Objectives to improve Foldit's performance.

Top groups

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  3. Avatar for Mercer_F20_BMB465_Crawford 43. Mercer_F20_BMB465_Crawford 4 pts. 8,579
  4. Avatar for Deleted group 44. Deleted group pts. 8,418
  5. Avatar for Columbia Univ CHEN 4800 Summer 2021 45. Columbia Univ CHEN 4800 Summer 2021 3 pts. 8,407
  6. Avatar for Team Canada 46. Team Canada 3 pts. 8,406
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  8. Avatar for GBHS BMAH kids 48. GBHS BMAH kids 3 pts. 8,145
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  10. Avatar for Titans of Biology 50. Titans of Biology 2 pts. 7,684
  1. Avatar for altaris 71. altaris Lv 1 79 pts. 11,203
  2. Avatar for tracybutt 72. tracybutt Lv 1 79 pts. 11,104
  3. Avatar for WBarme1234 73. WBarme1234 Lv 1 79 pts. 11,066
  4. Avatar for Crossed Sticks 74. Crossed Sticks Lv 1 79 pts. 11,056
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  6. Avatar for Argantyr 76. Argantyr Lv 1 78 pts. 10,989
  7. Avatar for jausmh 77. jausmh Lv 1 78 pts. 10,982
  8. Avatar for jawz101 78. jawz101 Lv 1 78 pts. 10,912
  9. Avatar for bamh 79. bamh Lv 1 77 pts. 10,901
  10. Avatar for Xartos 80. Xartos Lv 1 77 pts. 10,862

Comments

DoctorSockrates Lv 1

I was wondering when something like this would turn up. Glad to see an unrestricted proving ground for future projects.

KALYPSO Lv 1

Soap,,,,breaks the faty around the cell ,,,hmmmmm,,,puzzle that,,,just saying,,,try it

Bautho Lv 1

I don't know what is / I did wrong, but I designed a fold - perfectly fine, but after a while I wiggled, and one part of the protein will start to unfold (the helix is not a helix anymore) and the score goes down instead of up.
I sent the structure to scientists - if you could reproduce that behavior would be interesting! :)