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2424: Electron Density Reconstruction 80

Closed since about 2 years ago

Novice Overall Prediction Electron Density

Summary

Created
February 22, 2024
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. There's two copies of two chains each in this structure, two of which are quite short.

Sequence
A, C: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKAF. B,D: FRSKGEELFT

Top groups

  1. Avatar for Kotocycle 11. Kotocycle 1 pt. 34,920
  2. Avatar for BOINC@Poland 12. BOINC@Poland 1 pt. 34,740
  3. Avatar for BIOTF345 13. BIOTF345 1 pt. 29,766
  4. Avatar for SHELL 14. SHELL 1 pt. 29,061
  5. Avatar for BIOF215 15. BIOF215 1 pt. 28,324
  6. Avatar for AlphaFold 16. AlphaFold 1 pt. 21,059
  7. Avatar for BioInformatics2024 17. BioInformatics2024 1 pt. 19,640
  1. Avatar for arb 91. arb Lv 1 1 pt. 28,662
  2. Avatar for unmesh_bhole 92. unmesh_bhole Lv 1 1 pt. 28,597
  3. Avatar for harshit1234 93. harshit1234 Lv 1 1 pt. 28,445
  4. Avatar for timusinv 94. timusinv Lv 1 1 pt. 28,324
  5. Avatar for aditishimpi 95. aditishimpi Lv 1 1 pt. 28,155
  6. Avatar for Parv 96. Parv Lv 1 1 pt. 28,086
  7. Avatar for harshitw9 97. harshitw9 Lv 1 1 pt. 28,085
  8. Avatar for abhiram0824 98. abhiram0824 Lv 1 1 pt. 27,974
  9. Avatar for GhislainF 99. GhislainF Lv 1 1 pt. 27,716
  10. Avatar for almavher 100. almavher Lv 1 1 pt. 27,169

Comments

Serca Lv 1

Secondary structure prediction (JPred) is pretty close to what we see here.
LLLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLLLLLLLLLLLLLLLHHHHHHHHLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLL