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2424: Electron Density Reconstruction 80

Closed since about 2 years ago

Novice Overall Prediction Electron Density

Summary

Created
February 22, 2024
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. There's two copies of two chains each in this structure, two of which are quite short.

Sequence
A, C: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKAF. B,D: FRSKGEELFT

Top groups

  1. Avatar for Kotocycle 11. Kotocycle 1 pt. 34,920
  2. Avatar for BOINC@Poland 12. BOINC@Poland 1 pt. 34,740
  3. Avatar for BIOTF345 13. BIOTF345 1 pt. 29,766
  4. Avatar for SHELL 14. SHELL 1 pt. 29,061
  5. Avatar for BIOF215 15. BIOF215 1 pt. 28,324
  6. Avatar for AlphaFold 16. AlphaFold 1 pt. 21,059
  7. Avatar for BioInformatics2024 17. BioInformatics2024 1 pt. 19,640
  1. Avatar for janhavi 101. janhavi Lv 1 1 pt. 26,749
  2. Avatar for Divya1808 102. Divya1808 Lv 1 1 pt. 25,069
  3. Avatar for anisha_jj 103. anisha_jj Lv 1 1 pt. 24,770
  4. Avatar for Ankita.rch 104. Ankita.rch Lv 1 1 pt. 23,574
  5. Avatar for redrodeo 105. redrodeo Lv 1 1 pt. 23,143
  6. Avatar for Rishabkh 106. Rishabkh Lv 1 1 pt. 22,267
  7. Avatar for Animesh_Jawla 107. Animesh_Jawla Lv 1 1 pt. 21,734
  8. Avatar for AlphaFold2 108. AlphaFold2 Lv 1 1 pt. 21,059
  9. Avatar for dmacseng 109. dmacseng Lv 1 1 pt. 19,972
  10. Avatar for prattpradeev 110. prattpradeev Lv 1 1 pt. 19,686

Comments

Serca Lv 1

Secondary structure prediction (JPred) is pretty close to what we see here.
LLLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLLLLLLLLLLLLLLLHHHHHHHHLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLL