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2424: Electron Density Reconstruction 80

Closed since about 2 years ago

Novice Overall Prediction Electron Density

Summary

Created
February 22, 2024
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. There's two copies of two chains each in this structure, two of which are quite short.

Sequence
A, C: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKAF. B,D: FRSKGEELFT

Top groups

  1. Avatar for Kotocycle 11. Kotocycle 1 pt. 34,920
  2. Avatar for BOINC@Poland 12. BOINC@Poland 1 pt. 34,740
  3. Avatar for BIOTF345 13. BIOTF345 1 pt. 29,766
  4. Avatar for SHELL 14. SHELL 1 pt. 29,061
  5. Avatar for BIOF215 15. BIOF215 1 pt. 28,324
  6. Avatar for AlphaFold 16. AlphaFold 1 pt. 21,059
  7. Avatar for BioInformatics2024 17. BioInformatics2024 1 pt. 19,640
  1. Avatar for georg137 31. georg137 Lv 1 24 pts. 35,323
  2. Avatar for hansvandenhof 32. hansvandenhof Lv 1 23 pts. 35,271
  3. Avatar for Joanna_H 33. Joanna_H Lv 1 22 pts. 35,251
  4. Avatar for alcor29 34. alcor29 Lv 1 21 pts. 35,243
  5. Avatar for kitsoune 35. kitsoune Lv 1 19 pts. 35,074
  6. Avatar for ProfVince 36. ProfVince Lv 1 18 pts. 34,950
  7. Avatar for Ikuso 37. Ikuso Lv 1 17 pts. 34,920
  8. Avatar for ComputerMage 38. ComputerMage Lv 1 16 pts. 34,859
  9. Avatar for pfirth 39. pfirth Lv 1 15 pts. 34,800
  10. Avatar for RichGuilmain 40. RichGuilmain Lv 1 15 pts. 34,773

Comments

Serca Lv 1

Secondary structure prediction (JPred) is pretty close to what we see here.
LLLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLLLLLLLLLLLLLLLHHHHHHHHLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLL