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2424: Electron Density Reconstruction 80

Closed since about 2 years ago

Novice Overall Prediction Electron Density

Summary

Created
February 22, 2024
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model. There's two copies of two chains each in this structure, two of which are quite short.

Sequence
A, C: MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKAF. B,D: FRSKGEELFT

Top groups

  1. Avatar for Kotocycle 11. Kotocycle 1 pt. 34,920
  2. Avatar for BOINC@Poland 12. BOINC@Poland 1 pt. 34,740
  3. Avatar for BIOTF345 13. BIOTF345 1 pt. 29,766
  4. Avatar for SHELL 14. SHELL 1 pt. 29,061
  5. Avatar for BIOF215 15. BIOF215 1 pt. 28,324
  6. Avatar for AlphaFold 16. AlphaFold 1 pt. 21,059
  7. Avatar for BioInformatics2024 17. BioInformatics2024 1 pt. 19,640
  1. Avatar for jeet_lohiya 81. jeet_lohiya Lv 1 1 pt. 29,018
  2. Avatar for kitvb 82. kitvb Lv 1 1 pt. 28,993
  3. Avatar for Madis731 83. Madis731 Lv 1 1 pt. 28,984
  4. Avatar for aviral01 84. aviral01 Lv 1 1 pt. 28,970
  5. Avatar for Rilyhigg1 85. Rilyhigg1 Lv 1 1 pt. 28,921
  6. Avatar for riddhanya 86. riddhanya Lv 1 1 pt. 28,888
  7. Avatar for achira18 87. achira18 Lv 1 1 pt. 28,871
  8. Avatar for adi_prak 88. adi_prak Lv 1 1 pt. 28,827
  9. Avatar for yuvraj211 89. yuvraj211 Lv 1 1 pt. 28,819
  10. Avatar for Dhanush 90. Dhanush Lv 1 1 pt. 28,688

Comments

Serca Lv 1

Secondary structure prediction (JPred) is pretty close to what we see here.
LLLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLLLLLLLLLLLLLLLHHHHHHHHLLLLLLLEEEEEELLLLLLHHHHHHHHHHHLLLLHHHHHHHHHHHHLLLLEEEEEELHHHHHHHHHHHHHHHHHLLLLLEEEEELLLLLLLL