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2666: Electron Density Reconstruction 137

Closed since 6 months ago

Novice Overall Prediction Electron Density

Summary

Created
September 17, 2025
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model.

Sequence
MEYEITNYSERHTELPGHFIGLNTVDKLEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLI

Top groups

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  1. Avatar for Zhang Ruichong 11. Zhang Ruichong Lv 1 46 pts. 65,598
  2. Avatar for BootsMcGraw 12. BootsMcGraw Lv 1 42 pts. 65,572
  3. Avatar for meatexplosion 13. meatexplosion Lv 1 39 pts. 65,554
  4. Avatar for WBarme1234 14. WBarme1234 Lv 1 36 pts. 65,417
  5. Avatar for Aarav_Awasthi 15. Aarav_Awasthi Lv 1 33 pts. 65,405
  6. Avatar for gmn 16. gmn Lv 1 30 pts. 65,401
  7. Avatar for Galaxie 17. Galaxie Lv 1 27 pts. 65,275
  8. Avatar for dcrwheeler 18. dcrwheeler Lv 1 25 pts. 65,135
  9. Avatar for grogar7 19. grogar7 Lv 1 23 pts. 65,056
  10. Avatar for AlkiP0Ps 20. AlkiP0Ps Lv 1 20 pts. 65,055

Comments

LociOiling Lv 1

Still pre-release, but based on the sequence above, this one matches PDB 1W93 and 1W96, among others. We'll have to wait for the puzzle to see what the best match is.

LociOiling Lv 1

Upon close inspection, PDB 1W93 is an exact match. The key is missing residues DFRT, splitting the puzzle into two chains as far as AA Edit is concerned.