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2666: Electron Density Reconstruction 137

Closed since 6 months ago

Novice Overall Prediction Electron Density

Summary

Created
September 17, 2025
Expires
Max points
100
Description

The structure of this protein has already been solved and published, but close inspection suggests that there are some problems with the published solution. We'd like to see if Foldit players can use the same electron density data to reconstruct a better model.

Sequence
MEYEITNYSERHTELPGHFIGLNTVDKLEESPLRDFVKSHGGHTVISKILIANNGIAAVKEIRSVRKWAYETFGDDRTVQFVAMATPEDLEANAEYIRMADQYIEVPGGTNNNNYANVDLIVDIAERADVDAVWAGWGHASENPLLPEKLSQSKRKVIFIGPPGNAMRSLGDKISSTIVAQSAKVPCIPWSGTGVDTVHVDEKTGLVSVDDDIYQKGCCTSPEDGLQKAKRIGFPVMIKASEGGGGKGIRQVEREEDFIALYHQAANEIPGSPIFIMKLAGRARHLEVQLLADQYGTNISLFGRDCSVQRRHQKIIEEAPVTIAKAETFHEMEKAAVRLGKLVGYVSAGTVEYLYSHDDGKFYFLELNPRLQVEHPTTEMVSGVNLPAAQLQIAMGIPMHRISDIRTLYGMNPHSASEIDFEFKTQDATKKQRRPIPKGHCTACRITSEDPNDGFKPSGGTLHELNFRSSSNVWGYFSVGNNGNIHSFSDSQFGHIFAFGENRQASRKHMVVALKELSIRGDFRTTVEYLIKLLETEDFEDNTITTGWLDDLI

Top groups

  1. Avatar for Gargleblasters 11. Gargleblasters 1 pt. 63,431
  2. Avatar for SETI.Germany 12. SETI.Germany 1 pt. 63,134
  3. Avatar for Street Smarts 13. Street Smarts 1 pt. 60,517
  4. Avatar for Eὕρηκα! Heureka! 14. Eὕρηκα! Heureka! 1 pt. 60,245
  5. Avatar for BOINC@Poland 15. BOINC@Poland 1 pt. 60,004
  6. Avatar for Mahmut Oyunda 16. Mahmut Oyunda 1 pt. 54,381
  7. Avatar for People team 17. People team 1 pt. 19,398
  1. Avatar for Joanna_H 41. Joanna_H Lv 1 2 pts. 62,845
  2. Avatar for jamiexq 42. jamiexq Lv 1 2 pts. 61,824
  3. Avatar for abiogenesis 43. abiogenesis Lv 1 1 pt. 61,449
  4. Avatar for pfirth 44. pfirth Lv 1 1 pt. 61,032
  5. Avatar for Larini 45. Larini Lv 1 1 pt. 60,914
  6. Avatar for Mohoernchen 46. Mohoernchen Lv 1 1 pt. 60,856
  7. Avatar for Will the pill 47. Will the pill Lv 1 1 pt. 60,517
  8. Avatar for Hellcat6 48. Hellcat6 Lv 1 1 pt. 60,481
  9. Avatar for Savas 49. Savas Lv 1 1 pt. 60,245
  10. Avatar for DScott 50. DScott Lv 1 1 pt. 60,221

Comments

LociOiling Lv 1

Still pre-release, but based on the sequence above, this one matches PDB 1W93 and 1W96, among others. We'll have to wait for the puzzle to see what the best match is.

LociOiling Lv 1

Upon close inspection, PDB 1W93 is an exact match. The key is missing residues DFRT, splitting the puzzle into two chains as far as AA Edit is concerned.