Placeholder image of a protein
Icon representing a puzzle

439: H2N2 Flu Design Puzzle 1b

Closed since over 14 years ago

Intermediate Overall Design

Summary

Created
July 14, 2011
Expires
Max points
100
Description

This is the first of the many new exciting Flu puzzles David Baker mentioned in his blogpost. Our lab designed against the H1N1 subtype of the virus, but a related subtype with pandemic potential, H2N2, has different sidechains in this region that perturb binding. The goal is to design the interface of these designs so that it can bind to the H2 subtype of Influenza. This puzzle is worth 150 global points! If you are new to Foldit, make sure you have completed the Intro Puzzle 4-5 and Design Puzzles 6-1 through 6-4. We've tweaked some parameters since the last time you've seen this protein, so things should be a little different!

Top groups

  1. Avatar for TT-group 21. TT-group 1 pt. 7,298
  2. Avatar for name_in_progress 22. name_in_progress 1 pt. 7,294
  3. Avatar for hhv9 23. hhv9 1 pt. 6,455
  4. Avatar for Deleted group 24. Deleted group pts. 6,455
  5. Avatar for DSN @ Home 25. DSN @ Home 1 pt. 5,660
  6. Avatar for Richard Dawkins Foundation 26. Richard Dawkins Foundation 1 pt. 5,646
  1. Avatar for berus 111. berus Lv 1 6 pts. 7,327
  2. Avatar for Cerzax 112. Cerzax Lv 1 6 pts. 7,326
  3. Avatar for elesire 113. elesire Lv 1 6 pts. 7,326
  4. Avatar for SuperBEEP 114. SuperBEEP Lv 1 6 pts. 7,325
  5. Avatar for frostschutz 115. frostschutz Lv 1 6 pts. 7,323
  6. Avatar for Kevonni 116. Kevonni Lv 1 5 pts. 7,322
  7. Avatar for Bluefire526 117. Bluefire526 Lv 1 5 pts. 7,321
  8. Avatar for pmar 118. pmar Lv 1 5 pts. 7,321
  9. Avatar for Quark150 119. Quark150 Lv 1 5 pts. 7,320
  10. Avatar for pruneau_44 120. pruneau_44 Lv 1 5 pts. 7,320

Comments