Placeholder image of a protein
Icon representing a puzzle

460: Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate Overall Prediction

Summary

Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Top groups

  1. Avatar for Void Crushers
    1. Void Crushers
    100 pts. 10,577
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 91 pts. 10,474
  3. Avatar for foldeRNA 3. foldeRNA 81 pts. 10,470
  4. Avatar for Contenders 4. Contenders 73 pts. 10,467
  5. Avatar for Androids 5. Androids 65 pts. 10,465
  6. Avatar for Go Science 6. Go Science 58 pts. 10,445
  7. Avatar for Russian team 7. Russian team 52 pts. 10,381
  8. Avatar for Natural Abilities 8. Natural Abilities 46 pts. 10,339
  9. Avatar for Deleted group 9. Deleted group pts. 10,171
  10. Avatar for SQUID 10. SQUID 36 pts. 10,156
  1. Avatar for manu8170 131. manu8170 Lv 1 60 pts. 9,662
  2. Avatar for pmlkjn 132. pmlkjn Lv 1 60 pts. 9,662
  3. Avatar for Nicolien 133. Nicolien Lv 1 60 pts. 9,661
  4. Avatar for deus911 134. deus911 Lv 1 60 pts. 9,660
  5. Avatar for Emyryn 135. Emyryn Lv 1 59 pts. 9,657
  6. Avatar for Matter-Bender 136. Matter-Bender Lv 1 59 pts. 9,652
  7. Avatar for firejuggler 137. firejuggler Lv 1 59 pts. 9,648
  8. Avatar for nerdyshygirl 138. nerdyshygirl Lv 1 59 pts. 9,644
  9. Avatar for Deleted player 139. Deleted player pts. 9,633
  10. Avatar for The Ferminator 140. The Ferminator Lv 1 58 pts. 9,629

Comments

beta_helix Staff Lv 1

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.