Placeholder image of a protein
Icon representing a puzzle

460: Quest to the SOLVED Monkey Virus Protein

Closed since over 14 years ago

Intermediate Overall Prediction

Summary

Created
September 23, 2011
Expires
Max points
100
Description

The crystal structure of monomeric M-PMV retroviral protease, which causes AIDS in rhesus monkeys, has finally been released. You may have read about this protein in the news recently... so we thought we should post it again as a Quest to the Native. Once again we are giving you the 10 NMR models to work on, they are also in the Alignment Tool. After threading, make sure to press G to Align the Guide. We're sure you can get even closer to the native this time, and in less than 10 days!

Top groups

  1. Avatar for Void Crushers
    1. Void Crushers
    100 pts. 10,577
  2. Avatar for Anthropic Dreams 2. Anthropic Dreams 91 pts. 10,474
  3. Avatar for foldeRNA 3. foldeRNA 81 pts. 10,470
  4. Avatar for Contenders 4. Contenders 73 pts. 10,467
  5. Avatar for Androids 5. Androids 65 pts. 10,465
  6. Avatar for Go Science 6. Go Science 58 pts. 10,445
  7. Avatar for Russian team 7. Russian team 52 pts. 10,381
  8. Avatar for Natural Abilities 8. Natural Abilities 46 pts. 10,339
  9. Avatar for Deleted group 9. Deleted group pts. 10,171
  10. Avatar for SQUID 10. SQUID 36 pts. 10,156
  1. Avatar for pierrevz 151. pierrevz Lv 1 55 pts. 9,591
  2. Avatar for nmeddy@hotmail.com 152. nmeddy@hotmail.com Lv 1 55 pts. 9,589
  3. Avatar for Brewster 153. Brewster Lv 1 55 pts. 9,585
  4. Avatar for Savas 154. Savas Lv 1 55 pts. 9,585
  5. Avatar for monkry 155. monkry Lv 1 55 pts. 9,584
  6. Avatar for Mike Cassidy 156. Mike Cassidy Lv 1 54 pts. 9,582
  7. Avatar for Thallium 157. Thallium Lv 1 54 pts. 9,576
  8. Avatar for TheedMan 158. TheedMan Lv 1 54 pts. 9,575
  9. Avatar for Kariudo 159. Kariudo Lv 1 54 pts. 9,575
  10. Avatar for rws 160. rws Lv 1 53 pts. 9,573

Comments

beta_helix Staff Lv 1

This is the Quest to the Native version of Puzzle 390:
http://fold.it/portal/node/989012

Now that the protein has been solved (thanks to all of you), the PDB has posted the solution:
http://pdb.rcsb.org/pdb/explore.do?structureId=3SQF

For hints on how to use Partial Threading with the Alignment Tool, check out: http://fold.it/portal/node/989012#comment-9780

And if you weren't playing Foldit last December and want to see if you would have been able to get close to the native, you can always turn off the guide by press Shift-S.