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550: Pre-CASP blind Alignment Puzzle 2

Closed since almost 14 years ago

Intermediate Overall Prediction

Summary

Created
April 28, 2012
Expires
Max points
100
Description

To prepare for CASP 10 (which begins on May 1st) we want to practice for the Template-Based Modeling category by giving you some blind targets to work on. This template-based target is 102 residues and we are again giving you the top-predicted template from 3 different alignment programs (you'll notice that 2 of them are identical templates, but have different alignments) The secondary structure predictions are posted in the puzzle comments.

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Comments

beta_helix Staff Lv 1

Here is the sequence logo predicted by the SAM server.

H = helix
E = sheet
C = loop (or coil)

The taller the letter at each position, the higher the probability of that specific secondary structure for that amino acid.

For example, the Phenylalanine at residue 25 is mostly predicted to be part of a sheet. However, the Phenylalanine at residue 51 is predicted to be anything.