Placeholder image of a protein
Icon representing a puzzle

555: Symmetric Beta Core Design Puzzle 1

Closed since almost 14 years ago

Intermediate Overall Design Symmetry

Summary

Created
May 09, 2012
Expires
Max points
100
Description

The ...WXCXW... motif adopts a remarkably stable homodimer structure. In fact, it's so tiny, it is difficult to use as a building block for bioengineering; it needs to be larger but retain rigidity. Otherwise anything goes: beta sheets, alpha helix docking, rigid loops, you name it. We've given you 20 extra residues to play with. See what you can do! (Hint: select some residues, set secondary structure to sheet or helix, and hit Rebuild for some quick helices or sheets)

Top groups

  1. Avatar for HMT heritage 11. HMT heritage 10 pts. 9,483
  2. Avatar for Richard Dawkins Foundation 12. Richard Dawkins Foundation 8 pts. 9,452
  3. Avatar for Androids 13. Androids 6 pts. 9,432
  4. Avatar for Russian team 14. Russian team 4 pts. 9,423
  5. Avatar for Deleted group 15. Deleted group pts. 9,304
  6. Avatar for Freedom Folders 16. Freedom Folders 2 pts. 9,198
  7. Avatar for Eὕρηκα! Heureka! 17. Eὕρηκα! Heureka! 2 pts. 9,084
  8. Avatar for Piratenpartei Deutschland 18. Piratenpartei Deutschland 1 pt. 8,950
  9. Avatar for Deleted group 19. Deleted group pts. 8,933
  10. Avatar for Atlanta 20. Atlanta 1 pt. 8,927
  1. Avatar for tallguy-13088 71. tallguy-13088 Lv 1 27 pts. 9,463
  2. Avatar for Datstandin 72. Datstandin Lv 1 26 pts. 9,463
  3. Avatar for Museka 73. Museka Lv 1 26 pts. 9,461
  4. Avatar for Deleted player 74. Deleted player pts. 9,460
  5. Avatar for pvc78 75. pvc78 Lv 1 25 pts. 9,454
  6. Avatar for Tony Origami 76. Tony Origami Lv 1 24 pts. 9,454
  7. Avatar for aendgraend 77. aendgraend Lv 1 24 pts. 9,451
  8. Avatar for nemo7731 78. nemo7731 Lv 1 23 pts. 9,450
  9. Avatar for Ribo-soma 79. Ribo-soma Lv 1 23 pts. 9,449
  10. Avatar for Larry Pierce 80. Larry Pierce Lv 1 22 pts. 9,445

Comments

beta_helix Staff Lv 1

Because we want to preserve the frozen sheets and disulfide bond across the symmetric interface, we had to turn off the move tool and lock residue 7 as well.