Placeholder image of a protein
Icon representing a puzzle

555: Symmetric Beta Core Design Puzzle 1

Closed since almost 14 years ago

Intermediate Overall Design Symmetry

Summary

Created
May 09, 2012
Expires
Max points
100
Description

The ...WXCXW... motif adopts a remarkably stable homodimer structure. In fact, it's so tiny, it is difficult to use as a building block for bioengineering; it needs to be larger but retain rigidity. Otherwise anything goes: beta sheets, alpha helix docking, rigid loops, you name it. We've given you 20 extra residues to play with. See what you can do! (Hint: select some residues, set secondary structure to sheet or helix, and hit Rebuild for some quick helices or sheets)

Top groups

  1. Avatar for Koronan ChemistryUO Poland 21. Koronan ChemistryUO Poland 1 pt. 8,924
  2. Avatar for Nerdfighters 22. Nerdfighters 1 pt. 8,922
  3. Avatar for Czech National Team 23. Czech National Team 1 pt. 8,869
  4. Avatar for DSN @ Home 24. DSN @ Home 1 pt. 8,854
  5. Avatar for Trinity 25. Trinity 1 pt. 8,850
  6. Avatar for Team China 26. Team China 1 pt. 8,845
  7. Avatar for Friday Lab 27. Friday Lab 1 pt. 8,845
  8. Avatar for Skeptics Guide to the Universe 28. Skeptics Guide to the Universe 1 pt. 8,839
  1. Avatar for LavenderSky 41. LavenderSky Lv 1 49 pts. 9,553
  2. Avatar for krulon 42. krulon Lv 1 48 pts. 9,553
  3. Avatar for Petrifolder 43. Petrifolder Lv 1 47 pts. 9,540
  4. Avatar for anne romaine 44. anne romaine Lv 1 47 pts. 9,540
  5. Avatar for Bautho 45. Bautho Lv 1 46 pts. 9,538
  6. Avatar for itskimo 46. itskimo Lv 1 45 pts. 9,533
  7. Avatar for phi16 47. phi16 Lv 1 44 pts. 9,532
  8. Avatar for frood66 48. frood66 Lv 1 43 pts. 9,529
  9. Avatar for goastano 49. goastano Lv 1 42 pts. 9,528
  10. Avatar for bertro 50. bertro Lv 1 41 pts. 9,526

Comments

beta_helix Staff Lv 1

Because we want to preserve the frozen sheets and disulfide bond across the symmetric interface, we had to turn off the move tool and lock residue 7 as well.